Bellifill® is a unique injectable collagen filler with microspheres that can instantly smooth facial wrinkles (nasolabial folds) for beautiful, natural-looking correction that lasts.

Bellifill® is made of 80% collagen & 20% PMMA microspheres.

What is Bellifill® and what makes it unique?

It is distinctive

In the world of injectables, Bellafilll® is distinct. In addition to immediately adding volume to the skin to lift wrinkles known as smile lines, Bellafilll® re-creates the firm structure of younger-looking skin by supporting production of your body’s own collagen.

Approved by the FDA

Bellafilll® has been approved for the correction of facial wrinkles known as nasolabial folds or smile lines since 2006. Bellafilll® requires a skin test to identify patients who may be sensitive to the lidocaine or bovine collagen in Bellafilll®, which affected less than 1% in the Bellafilll® clinical trial.

Proven safe

Bellafilll® isn’t just an exceptional cosmetic treatment option. Bellafilll®’s safety profile is comparable to the temporary fillers you are already familiar with and perhaps already using.

Bellafilll® is a polymethylmethacrylate (PMMA) collagen filler

  • See visible correction with the very first treatment.
  • The collagen in Bellafilll® provides immediate volume and lift while the PMMA microspheres remain in place and create a matrix that supports collagen production in your skin for lasting improvement.

Gel immediately after injection 80% collagen gel and 20% PMMA microspheres

4 months after injection Collagen tissue matrix and blood vessels have formed around PMMA

Filler enhancement that makes economic sense

Most patients can expect to maintain the correction they see early after treatment. However, every patient’s skin is unique and therefore we recommend starting slowly with a conservative amount and continuing treatment as needed to get the best correction, correction that lasts.

Is Bellafilll® right for me?

It’s a difference you can feel

Treatment with Bellafilll® is very similar to treatment with conventional fillers. Bellafilll® immediately adds volume to wrinkles known as smile lines for a smoother, more youthful appearance. In addition, Bellafilll® re-creates the firm structure of younger-looking skin by supporting production of your body’s own collagen. Bellafilll® requires a skin test to identify those patients who may have an allergy to lidocaine or bovine collagen.

The beautiful benefits of Bellafilll®

  • Immediate and lasting improvement for wrinkles known as smile lines.
  • Injection comfort with 0.3% lidocaine.
  • Simple, in-office treatment with little to no downtime. You can immediately resume normal activities.
  • Helps replace lost collagen by working with your body’s natural processes.
  • Comparable safety to other injectable fillers2.

What’s your wrinkle type?

Wrinkles caused by repetitive movement

Repeated movement of the facial skin may create wrinkles. These types of wrinkles are “dynamic.” Age is a factor, but repeated facial movements, such as frowning or squinting, can also create lines, which means they may develop even in younger adults. These wrinkles are not candidates for Bellafilll® treatment.

Wrinkles caused by volume loss and gravity

Over time, we lose volume in our faces, increasing the chances for wrinkles and folds to appear. The fat pads in our cheeks may slide downward toward the mouth, which can cause the skin to wrinkle or fold, creating the “smile lines” from your nose to the corners of your mouth (nasolabial folds).

Bellafilll® can treat wrinkles caused by lost volume

Treatment with Bellafilll® adds youthful volume and fullness to the skin to effectively lift the wrinkle up to the level of the surrounding skin, with lasting correction. Imagine how you will look after treatment!

What makes Bellafill® work?

Patients who have a positive reaction to the Bellafilll® skin test, a history of severe allergies, known bovine collagen allergies, are allergic to lidocaine, prone to thick scar formation and/or excessive scarring should not receive Bellafilll®.

How Bellafill® works

Artefill® is placed below the depression using a fine needle.

Artefill® is placed below the depression using a fine needle.

Bellafilll® replaces lost volume in the skin below the wrinkle for correction that is immediate and lasting. The injectable gel is comprised of 80% purified collagen and 20% PMMA (polymethylmethacrylate) microspheres. The tiny microspheres are half the diameter of a human hair, so small that they are virtually invisible to the eye.

And keeps on working

The injectable gel immediately adds volume to the skin to lift and smooth out wrinkles.

The injectable gel immediately adds volume to the skin to lift and smooth out wrinkles.

Bellafilll® is different. It restores rather than just fills for natural enduring results. In clinical studies, efficacy was observed out to 12 months. (Primary efficacy endpoint was at 6 months.)

The Bellafilll® difference

Beauty that lasts

Bellafilll® offers an important difference to patients who know filler rejuvenation can be very costly. What if, instead of just filling, you could actually restore? Bellafilll® is your answer.

Proven safe. Proven smart

Bellafilll® isn’t just an exceptional cosmetic treatment option. Bellafilll®’s safety profile is comparable to the temporary fillers you are already familiar with and perhaps already using.

Look younger for longer, naturally

Bellafilll® provides a microscopic ‘matrix’ to support your body’s own natural collagen production, and ultimately strengthen the layers of the skin. This provides the support needed for wrinkle correction and younger-looking skin, with results that last4. In clinical trials, Bellafilll® showed significant improvement in smile lines at 3 months and 6 months after treatment, and continued to show improvement at 12 months.

Safety Information

Bellafilll® is FDA and Health Canada approved for the correction of facial wrinkles known as nasolabial folds or smile lines. Patients who have a positive reaction to the Artefill skin test, a history of severe allergies, known bovine collagen allergies, are allergic to lidocaine, prone to thick scar formation and/or excessive scarring should not receive Bellafilll®. Mild swelling and redness can occur at the treatment site but generally subside after 24 hours. The safety of Bellafilll® for use during pregnancy, breastfeeding or in patients under 18 has not been established. Long-term safety and effectiveness of Bellafilll® beyond one year has not been established. For more Safety Information please consult with your physician and the patient labeling.

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